Ampullosporin A
Ampullosporin A is a peptaibol-type polypeptide that can be isolated from the fungus Sepedonium ampullosporum HKI-0053, exhibiting neuroleptic-like activity. Ampullosporin A can inhibit hyperactivity induced by NMDA receptor antagonist MK-801 and ameliorate social behavior abnormalities caused by subchronic drug treatment. Ampullosporin A alters the activity of glutamate receptors without affecting dopamine D1 and D2 receptors[1].
Product Specifications
CAS Number
197960-94-4
UNSPSC
12352005
Target
IGluR
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Smiles
CC(C)C[C@@H](CO)NC([C@H](CCC(N)=O)NC(C(C)(C)NC([C@H](CC(C)C)NC([C@H](CCC(N)=O)NC(C(C)(C)NC(C(C)(C)NC(C(C)(C)NC([C@H](CCC(N)=O)NC(C(C)(C)NC([C@H](CC(C)C)NC(C(C)(C)NC(C(C)(C)NC([C@H](C)NC([C@@H](NC(C)=O)CC1=CNC2=CC=CC=C12)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O
Molecular Formula
C77H127N19O19
Molecular Weight
1622.95
References & Citations
[1]Berek I, et al. Ampullosporin A, a peptaibol from Sepedonium ampullosporum HKI-0053 with neuroleptic-like activity[J]. Behavioural brain research, 2009, 203 (2) : 232-239.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC740391-500 1x 500 µL
CD81 / TAPA-1 (1.3.3.22), CF740 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC740679-500 1x 500 µL
CD171 / L1CAM (L1 Cell Adhesion Molecule) (UJ127), CF740 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
