Nidulalin A
Nidulalin A is a DNA topoisomerase II inhibitor with an IC50 of 2.2 μM. Nidulalin A has an IC50 of 172 μM for DNA topoisomerase I. Nidulalin A has certain cytotoxicity[1].
Product Specifications
CAS Number
[162901-86-2]
UNSPSC
12352005
Target
Topoisomerase
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Others
Smiles
COC([C@]12C(C(C3=C(O)C=C(C)C=C3O2)=O)=CC=C[C@H]1O)=O
Molecular Formula
C16H14O6
Molecular Weight
302.28
References & Citations
[1]Sato S, et al. Inhibition of DNA topoisomerases by nidulalin A derivatives. Biol Pharm Bull. 2000 Apr;23 (4) :511-2.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Curated Selection
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