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Protohypericin (Standard)

Protohypericin is a compound that can be extracted from Hypericum perforatum. Protohypericin has low photocytotoxicity but can be efficiently photoconverted into Hypericin with high phototoxicity under visible light. Protohypericin can be used in cancer research[1][2][3][4].

Product Specifications

CAS Number

548-03-8

UNSPSC

12352005

Target

Drug Intermediate

Related Pathways

Others

Field of Research

Cancer

Smiles

O=C(C1=C(O)C=C(C)C=C1C2=C34)C3=C(O)C=C(O)C4=C5C(O)=CC(O)=C6C(C7=C(O)C=C(C)C=C7C2=C65)=O

Molecular Formula

C30H18O8

Molecular Weight

506.46

References & Citations

[1]Baugh SF. Simultaneous determination of protopseudohypericin, pseudohypericin, protohypericin, and hypericin without light exposure. J AOAC Int. 2005 Nov-Dec;88 (6) :1607-12.|[2]Liu X, et al. Tumor necrosis targeted radiotherapy of non-small cell lung cancer using radioiodinated protohypericin in a mouse model. Oncotarget. 2015 Sep 22;6 (28) :26400-10.|[3]Kamuhabwa AR, et al. In vitro transport and uptake of protohypericin and hypericin in the Caco-2 model. Int J Pharm. 1999 Oct 15;188 (1) :81-6.|[4]Delaey EM, et al. Photocytotoxicity of protohypericin after photoconversion to hypericin. Planta Med. 1999 Dec;65 (8) :719-22.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Frequently Asked Questions

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