Matairesinol-d6

Matairesinol-d6 is the deuterium labeled Matairesinol. Matairesinol confers anti-allergic effects in an allergic dermatitis mouse model. DfE-induced changes in IL-4 and IFN-γ mRNA expression in the ears of NC/Nga mice were reversed by matairesinol application[1].

Product Specifications

CAS Number

[1346600-02-9]

UNSPSC

12352005

Target

Endogenous Metabolite; Isotope-Labeled Compounds

Related Pathways

Metabolic Enzyme/Protease; Others

Field of Research

Infection

Solubility

10 mM in DMSO

Smiles

C([C@H]1[C@H](CC2=C(C(OC)=C(O)C(=C2[2H])[2H])[2H])C(=O)OC1)C3=C(C(OC)=C(O)C(=C3[2H])[2H])[2H]

Molecular Formula

C20H16D6O6

Molecular Weight

364.42

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Sung YY, Lee AY, Kim HK. Forsythia suspensa fruit extracts and the constituent matairesinol confer anti-allergic effects in an allergic dermatitis mouse model. J Ethnopharmacol. 2016;187:49-56.