Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

D-chiro-Inositol (Standard)

D-chiro-Inositol is a stereoisomer of inositol that exhibits activities such as improving glucose metabolism, anti-tumor effects, anti-inflammatory properties, and antioxidant activity. D-chiro-Inositol effectively alleviates cholestasis by enhancing bile acid secretion and reducing oxidative stress. D-chiro-Inositol improves insulin resistance, lowers hyperglycemia and circulating insulin levels, reduces serum androgen levels, and ameliorates some metabolic abnormalities associated with X syndrome by mimicking the action of insulin. Additionally, D-chiro-Inositol can induce a reduction in pro-inflammatory factors (such as Nf-κB) and cytokines (such as TNF-α), thereby exerting anti-inflammatory effects. D-chiro-Inositol may be used in the study of liver cirrhosis, breast cancer, type 2 diabetes, and polycystic ovary syndrome[1][2][3][4][5][6][7][8][9].

Product Specifications

CAS Number

643-12-9

UNSPSC

12352211

Target

Endogenous Metabolite; FOXO; Microtubule/Tubulin; NF-κB; TNF Receptor

Related Pathways

Apoptosis; Cell Cycle/DNA Damage; Cytoskeleton; Metabolic Enzyme/Protease; NF-κB

Field of Research

Metabolic Disease

Smiles

O[C@H]1[C@@H]([C@@H]([C@H]([C@@H]([C@H]1O)O)O)O)O

Molecular Formula

C6H12O6

Molecular Weight

180.16

References & Citations

[1]Ostlund RE Jr, et al. A stereospecific myo-inositol/D-chiro-inositol transporter in HepG2 liver cells. Identification with D-chiro-[3-3H]inositol. J Biol Chem. 1996 Apr 26;271 (17) :10073-8.|[2]Zhao SS, et al. D-chiro-inositol effectively attenuates cholestasis in bile duct ligated rats by improving bile acidsecretion and attenuating oxidative stress. Acta Pharmacol Sin. 2018 Feb;39 (2) :213-221.|[3]Cheng F, et al. chiro-Inositol Ameliorates High Fat Diet-Induced Hepatic Steatosis and Insulin Resistance viaPKCε-PI3K/AKT Pathway. J Agric Food Chem. 2019 May 29;67 (21) :5957-5967.|[4]Kim Y, et al. Inhibitory effect of D-chiro-inositol on both growth and recurrence of breast tumor from MDA-MB-231 cancer cells[J]. Natural Product Sciences, 2017, 23 (1) : 35-39.|[5]Gambioli R, et al. New insights into the activities of D-chiro-inositol: a narrative review[J]. Biomedicines, 2021, 9 (10) : 1378.|[6]Iuorno M J, et al. Effects of d-chiro-inositol in lean women with the polycystic ovary syndrome[J]. Endocrine Practice, 2002, 8 (6) : 417-423.|[7]Pintaudi B, et al. The effectiveness of Myo‐inositol and D‐chiro inositol treatment in type 2 diabetes[J]. International journal of endocrinology, 2016, 2016 (1) : 9132052.|[8]Larner J, et al. D‐chiro‐inositol–its functional role in insulin action and its deficit in insulin resistance[J]. Journal of Diabetes Research, 2002, 3 (1) : 47-60.|[9]Fortis-Barrera Á, et al. C ucurbita ficifolia Bouché (Cucurbitaceae) and D-chiro-inositol modulate the redox state and inflammation in 3T3-L1 adipocytes[J]. Journal of Pharmacy and Pharmacology, 2013, 65 (10) : 1563-1576.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

SULT1A1 Human Gene Knockout Kit (CRISPR)
KN401601 1 Kit

SULT1A1 Human Gene Knockout Kit (CRISPR)

Sign In for Pricing
View Details
p400 (EP400) Rabbit Polyclonal Antibody
TA375915 100 µL

p400 (EP400) Rabbit Polyclonal Antibody

Sign In for Pricing
View Details
Human LCE6A activation kit by CRISPRa
GA118565 1 Kit

Human LCE6A activation kit by CRISPRa

Sign In for Pricing
View Details
IL24 Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI4D1]
TA809389AM 100 µL

IL24 Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI4D1]

Sign In for Pricing
View Details
Tprkb (BC027413) Mouse Tagged ORF Clone
MG201201 10 µg

Tprkb (BC027413) Mouse Tagged ORF Clone

Sign In for Pricing
View Details
PSD95 Recombinant Rabbit Monoclonal Antibody [SR38-09]
ET1602-20 100 µL

PSD95 Recombinant Rabbit Monoclonal Antibody [SR38-09]

Sign In for Pricing
View Details