Naringenin chalcone (Standard)

Naringenin chalcone (Standard) is an analytical standard of Naringenin chalcone. This product is intended for research and analytical applications. Naringenin chalcone is an orally active intermediate in the biosynthesis of flavonols. Naringenin chalcone induces apoptosis. Naringenin chalcone inhibits the production of MCP-1 and NO. Naringenin chalcone exhibits anticancer activity against glioblastoma. Naringenin chalcone has anti-inflammatory and anti-allergic properties.

Product Specifications

CAS Number

[73692-50-9]

UNSPSC

12352005

Target

Apoptosis; Drug Intermediate; NO Synthase; Reference Standards

Related Pathways

Apoptosis; Immunology/Inflammation; Others

Field of Research

Inflammation/Immunology

Smiles

OC(C=C1)=CC=C1/C=C/C(C2=C(C=C(O)C=C2O)O)=O

Molecular Formula

C15H12O5

Molecular Weight

272.25

References & Citations

[1]Escribano-Ferrer E, et al. In Vivo Anti-inflammatory and Antiallergic Activity of Pure Naringenin, Naringenin Chalcone, and Quercetin in Mice.J Nat Prod. 2019 Feb 22;82 (2) :177-182.|[2]Iwamura C, Shinoda K, Yoshimura M, Watanabe Y, Obata A, Nakayama T. Naringenin chalcone suppresses allergic asthma by inhibiting the type-2 function of CD4 T cells. Allergol Int. 2010;59 (1) :67-73. |[3]Hirai S, Kim YI, Goto T, et al. Inhibitory effect of naringenin chalcone on inflammatory changes in the interaction between adipocytes and macrophages. Life Sci. 2007;81 (16) :1272-1279.