Prunetin (Standard)

Prunetin, an O-methylated isoflavone, possesses anti-inflammatory activity. Prunetin is a potent human aldehyde dehydrogenases inhibitor[1][2].

Product Specifications

CAS Number

[552-59-0]

UNSPSC

12352005

Target

Aldehyde Dehydrogenase (ALDH)

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Inflammation/Immunology

Smiles

O=C1C(C2=CC=C(O)C=C2)=COC3=CC(OC)=CC(O)=C13

Molecular Formula

C16H12O5

Molecular Weight

284.26

References & Citations

[1]Hu H, et al. Prunetin inhibits lipopolysaccharide-induced inflammatory cytokine production and MUC5AC expression by inactivating the TLR4/MyD88 pathway in human nasal epithelial cells. Biomed Pharmacother. 2018 Oct;106:1469-1477.|[2]Sheikh S, et al. Allosteric inhibition of human liver aldehyde dehydrogenase by the isoflavone prunetin. Biochem Pharmacol. 1997 Feb 21;53 (4) :471-8.