1-Monomyristin (Standard)
1-Monomyristin, extracted from Serenoa repens, inhibits the hydrolysis of 2-oleoylglycerol (IC50=32 μM) and fatty acid amide hydrolase (FAAH) activity (IC50=18 μM) . 1-Monomyristin shows antibacterial activity against Staphylococcus aureus and Aggregatibacter actinomycetemcomitans and also antifungal activity against Candida albicans[1][2][3].
Product Specifications
CAS Number
589-68-4
UNSPSC
12352211
Target
Autophagy; Bacterial; Endogenous Metabolite; FAAH; Fungal
Related Pathways
Anti-infection; Autophagy; Metabolic Enzyme/Protease; Neuronal Signaling
Field of Research
Infection
Smiles
CCCCCCCCCCCCCC(OCC(O)CO)=O
Molecular Formula
C17H34O4
Molecular Weight
302.45
References & Citations
[1]Shimada H, et al. Biologically active acylglycerides from the berries of saw-palmetto (Serenoa repens) . J Nat Prod. 1997 Apr;60 (4) :417-8.|[2]Vandevoorde S, et al. Influence of the degree of unsaturation of the acyl side chain upon the interaction of analogues of 1-arachidonoylglycerol with monoacylglycerol lipase and fatty acid amide hydrolase. Biochem Biophys Res Commun. 2005 Nov 11;337 (1) :104-9.|[3]Jumina, et al. Monomyristin and Monopalmitin Derivatives: Synthesis and Evaluation as Potential Antibacterial and Antifungal Agents. Molecules. 2018 Nov 29;23 (12) . pii: E3141
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
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