Tomatidine (Standard)
Tomatidine acts as an anti-inflammatory agent by blocking NF-κB and JNK signaling[1]. Tomatidine activates autophagy either in mammal cells or C elegans[2].
Product Specifications
CAS Number
77-59-8
UNSPSC
12352005
Target
Autophagy; Endogenous Metabolite; JNK; NF-κB
Related Pathways
Autophagy; MAPK/ERK Pathway; Metabolic Enzyme/Protease; NF-κB
Field of Research
Inflammation/Immunology; Cardiovascular Disease
Smiles
[H][C@]1(O[C@]2(NC[C@@H](C)CC2)[C@H]3C)C[C@@]4([H])[C@]5([H])CC[C@@]6([H])C[C@@H](O)CC[C@]6(C)[C@@]5([H])CC[C@]4(C)[C@]13[H]
Molecular Formula
C27H45NO2
Molecular Weight
415.65
References & Citations
[1]Chiu FL, et al. Tomatidine inhibits iNOS and COX-2 through suppression of NF-kappaB and JNK pathways in LPS-stimulated mouse macrophages. FEBS Lett. 2008 Jul 9;582 (16) :2407-12.|[2]Anil Ahsan, et al. Tomatidine Protects Against Ischemic Neuronal Injury by Improving Lysosomal Function. Eur J Pharmacol. 2020 Jun 21;173280.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
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