Musk ketone (Standard)

Bulleyaconitine A (Standard) is the analytical standard of Bulleyaconitine A. This product is intended for research and analytical applications. 0

Product Specifications

CAS Number

[81-14-1]

UNSPSC

12352005

Target

Akt; Apoptosis; Cytochrome P450; PI3K; Reference Standards

Related Pathways

Apoptosis; Metabolic Enzyme/Protease; Others; PI3K/Akt/mTOR

Field of Research

Neurological Disease

Smiles

CC(C1=C(C)C([N+]([O-])=O)=C(C(C)(C)C)C([N+]([O-])=O)=C1C)=O

Molecular Formula

C14H18N2O5

Molecular Weight

294.31

References & Citations

[1]Yamagishi T, et al. Identification of musk xylene and musk ketone in freshwater fish collected from the Tama River, Tokyo. Bull Environ Contam Toxicol. 1981 May;26 (5) :656-62. |[2]Mersch-Sundermann V, et al. Musk ketone enhances benzo (a) pyrene induced mutagenicity in human derived Hep G2 cells. Mutat Res. 2001 Aug 22;495 (1-2) :89-96. |[3]Zhou Z, et al. Musk Ketone Induces Neural Stem Cell Proliferation and Differentiation in Cerebral Ischemia via Activation of the PI3K/Akt Signaling Pathway. Neuroscience. 2020 May 21;435:1-9.|[4]Lehman-McKeeman LD, et al. Effects of musk xylene and musk ketone on rat hepatic cytochrome P450 enzymes. Toxicol Lett. 1999 Dec 20;111 (1-2) :105-15.|[5]An J, et al. Musk ketone induces apoptosis of gastric cancer cells via downregulation of sorbin and SH3 domain containing 2. Mol Med Rep. 2021 Jun;23 (6) :450.