Dauricinoline

Dauricinoline is an orally active NF-κB inhibitor that can significantly inhibit NF-κB activation induced by TNF-α. Dauricinoline exhibits certain anti-inflammatory activity and can be used in the research of inflammatory diseases such as lung inflammation[1].

Product Specifications

CAS Number

[30984-80-6]

UNSPSC

12352005

Target

NF-κB

Related Pathways

NF-κB

Field of Research

Inflammation/Immunology

Smiles

OC1=CC2=C([C@@H](CC3=CC=C(O)C(OC4=CC=C(C[C@H]5N(C)CCC6=C5C=C(OC)C(OC)=C6)C=C4)=C3)N(C)CC2)C=C1OC

Molecular Formula

C37H42N2O6

Molecular Weight

610.74

References & Citations

[1]Sun D, et al. Identification of nuclear factor-κB inhibitors in the folk herb Rhizoma Menispermi via bioactivity-based ultra-performance liquid chromatography/quadrupole time-of-flight mass spectrometry analysis. BMC Complement Altern Med. 2014 Sep 25;14:356.