Urushiol (15:3)

Ursolic acid (15:3) (Compound 4) is a type of resiniferatoxin compound that can be found in the leaves of the tree Rhus verniciflua. Ursolic acid (15:3) exhibits moderate inhibitory activity against HIV-1 reverse transcriptase (b HIV-1 reverse transcriptase), with an IC50 value of 55.36 μM. Ursolic acid (15:3) shows strong cytotoxicity against both PC-3 and MRC-5 cells. Ursolic acid (15:3) can be used in the research of anti-HIV-1 infection and prostate cancer[1].

Product Specifications

CAS Number

[83543-37-7]

Product Name Alternative

3-[8' (Z), 11' (Z), 14'-Pentadecatrienyl] catechol

UNSPSC

12352005

Target

HIV; Reverse Transcriptase

Related Pathways

Anti-infection

Field of Research

Cancer; Infection

Smiles

OC1=CC=CC(CCCCCCC/C=C\C/C=C\CC=C)=C1O

Molecular Formula

C21H30O2

Molecular Weight

314.46

References & Citations

[1]Kadokura K, et al. Novel urushiols with human immunodeficiency virus type 1 reverse transcriptase inhibitory activity from the leaves of Rhus verniciflua. J Nat Med. 2015 Jan;69 (1) :148-53.