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4H-Tomentosin

4H-Tomentosin is a mixed-competitive type soluble epoxide hydrolase (sEH) inhibitor with an IC50 of 6.84 μM and a Ki of 7.02 μM. 4H-Tomentosin interacts with sEH by forming hydrogen bonds with Tyr343, Ile363, and Tyr383[1].

Product Specifications

CAS Number

68776-19-2

UNSPSC

12352005

Target

Epoxide Hydrolase

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Cardiovascular Disease

Smiles

O=C1OC2CC(C)C(CCC(C)O)=CCC2C1=C

Molecular Formula

C15H22O3

Molecular Weight

250.33

References & Citations

[1]He X, et al. Natural soluble epoxide hydrolase inhibitors from Inula helenium and their interactions with soluble epoxide hydrolase. Int J Biol Macromol. 2020 Apr 29:S0141-8130 (20) 33090-7.

Shipping Conditions

Room temperature

Scientific Category

Natural Products

Clinical Information

No Development Reported

Frequently Asked Questions

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