Cimicifugic acid A
Cimicifugic acid A is a cytotoxic caffeic acid derivative that can be isolated from the rhizomes of Cimicifuga heracleifolia. Cimicifugic acid A shows cytotoxic activity against cancer cells, and increases expression of cleaved PARP, thereby exhibiting pro-apoptotic activity. Cimicifugic acid A can be used for colon cancer research[1].
Product Specifications
CAS Number
[205114-65-4]
UNSPSC
12352005
Target
Apoptosis; PARP
Related Pathways
Apoptosis; Cell Cycle/DNA Damage; Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
OC(C=C1C[C@@](C(O)=O)(O)[C@@H](C(O)=O)OC(/C=C/C2=CC(OC)=C(C=C2)O)=O)=C(C=C1)O
Molecular Formula
C21H20O11
Molecular Weight
448.38
References & Citations
[1]Yim SH, et al. Cytotoxic caffeic acid derivatives from the rhizomes of Cimicifuga heracleifolia. Arch Pharm Res. 2012 Sep;35 (9) :1559-65.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
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