Tricetinidin (chloride)

Tricetinidin chloride is an antioxidant. Tricetinidin chloride protects rat renal cells against oxidative stress and DNA damage by reducing ROS production, increasing GSH levels, restoring mitochondrial membrane potential, and upregulating HO-1 expression. Tricetinidin chloride also inhibits the expression of IgE receptors on human mast cells. Tricetinidin chloride can be used in the research of inflammatory and allergic diseases[1][2].

Product Specifications

CAS Number

[65618-21-5]

UNSPSC

12352005

Target

Fc Receptor (FcR) ; Heme Oxygenase (HO) ; Reactive Oxygen Species (ROS)

Related Pathways

Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Field of Research

Inflammation/Immunology

Smiles

[Cl-].OC1=CC(O)=C2C=CC(=[O+]C2=C1)C=3C=C(O)C(O)=C(O)C3

Molecular Formula

C15H11ClO6

Molecular Weight

322.70

References & Citations

[1]Bankoglu EE, et al. Protective effects of tricetinidin against oxidative stress inducers in rat kidney cells: A comparison with delphinidin and standard antioxidants. Food Chem Toxicol. 2018 Nov;121:549-557.|[2]Tamura S, et al. New inhibitors for expression of IgE receptor on human mast cell. Bioorg Med Chem Lett. 2010 Apr 1;20 (7) :2299-302.