5,6,7-Trihydroxy-4'-methoxyflavone

5,6,7-Trihydroxy-4'-methoxyflavone is a flavonoid and a weak inhibitor of xanthine oxidase. 5,6,7-Trihydroxy-4'-methoxyflavone possesses antithrombotic and antioxidant activities. 5,6,7-Trihydroxy-4'-methoxyflavone has an IC50 value of 25.29 µM for DPPH free radical scavenging. 5,6,7-Trihydroxy-4'-methoxyflavone can also inhibit H2O2-induced damage to PC12 cells. 5,6,7-Trihydroxy-4'-methoxyflavone is applicable for the research of diseases such as cerebrovascular disorders[1][2].

Product Specifications

CAS Number

6563-66-2

Product Name Alternative

4'-O-Methylscutellarein

UNSPSC

12352005

Target

Xanthine Oxidase

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Cardiovascular Disease; Neurological Disease

Smiles

O=C1C=C(C2=CC=C(OC)C=C2)OC3=CC(O)=C(C(O)=C13)O

Molecular Formula

C16H12O6

Molecular Weight

300.26

References & Citations

[1]Khan R, et al. Phenolic substances of Caragana conferta and their superoxide scavenging activity. Chemistry of Natural Compounds, 2010, 46 (5) : 722-725.|[2]Shi ZH, et al. Synthesis and biological evaluation of methylated scutellarein analogs based on metabolic mechanism of scutellarin in vivo. Eur J Med Chem. 2015 Dec 1;106:95-105.