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Cholic acid 3-sulfate

Cholic acid 3-sulfate is the sulfated metabolite of Cholic acid , produced by liver enzyme sulfotransferase-2A1. Cholic acid 3-sulfate is less toxic than the parent compound, thus serving as a detoxification pathway for bile acids. Cholic acid 3-sulfate does not have the effect of stimulating intestinal secretion[1].

Product Specifications

CAS Number

66167-89-3

UNSPSC

12352211

Target

Drug Metabolite

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Smiles

O[C@H]1[C@@]2([H])[C@@]3([H])[C@@]([C@@](CC3)([H])[C@H](C)CCC(O)=O)([C@H](C[C@]2([H])[C@@]4([C@](C[C@@H](CC4)OS(=O)(O)=O)([H])C1)C)O)C

Molecular Formula

C24H40O8S

Molecular Weight

488.63

References & Citations

[1]Hofmann AF, et al. Altered bile acid metabolism in childhood functional constipation: inactivation of secretory bile acids by sulfation in a subset of patients. J Pediatr Gastroenterol Nutr. 2008 Nov;47 (5) :598-606.

Shipping Conditions

Room temperature

Scientific Category

Natural Products

Clinical Information

No Development Reported

Frequently Asked Questions

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