Myristinin B/C
Myristinin B/C is a mixture of Myristinin B and Myristinin C. Myristinin B/C is a flavan compound found in Horsfieldia amygdaline and Myristica cinnamomea. Myristinin B/C can selectively inhibit COX-2 activity with an IC50 of 2.1 μg/mL. Myristinin B/C can reduce the production of prostaglandin E2 (PGE2) and inhibit phospholipase A2 (PLA2), thereby blocking the release of inflammatory mediators. Myristinin B/C can inhibit Candida albicans with an IC50 of 6 μg/mL. Myristinin B/C can be used for the research of inflammation and infection, such as rheumatoid arthritis[1].
Product Specifications
UNSPSC
12352005
Target
COX; Fungal; Prostaglandin Receptor
Related Pathways
Anti-infection; GPCR/G Protein; Immunology/Inflammation
Field of Research
Infection; Inflammation/Immunology
Smiles
OC1=C([C@@H]2C3=CC=C(C=C3O[C@@H](C2)C4=CC=C(O)C=C4)O)C(O)=CC(O)=C1C(CCCCCCCCCCC)=O
Molecular Formula
C33H40O7
Molecular Weight
548.67
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
COX-2
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