Circumdatin C
Circumdatin C is an alkaloid. Circumdatin C shows inhibitory effects against LPS-stimulated NO production. Circumdatin C inhibits AChE activity with an IC50 value of 13.9 μM. Circumdatin C can be used in the research of Alzheimer's disease[1].
Product Specifications
CAS Number
223130-61-8
UNSPSC
12352005
Target
Cholinesterase (ChE) ; NO Synthase
Related Pathways
Immunology/Inflammation; Neuronal Signaling
Field of Research
Inflammation/Immunology; Neurological Disease
Smiles
O=C1N2C3=CC=C(O)C=C3C(N[C@H](C2=NC4=CC=CC=C41)C)=O
Molecular Formula
C17H13N3O3
Molecular Weight
307.30
References & Citations
[1]Zhang C, et al. Circumdatin D Exerts Neuroprotective Effects by Attenuating LPS-Induced Pro-Inflammatory Responses and Downregulating Acetylcholinesterase Activity In Vitro and In Vivo. Front Pharmacol. 2020 May 25;11:760.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
AChE
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