Circumdatin C

Circumdatin C is an alkaloid. Circumdatin C shows inhibitory effects against LPS-stimulated NO production. Circumdatin C inhibits AChE activity with an IC50 value of 13.9 μM. Circumdatin C can be used in the research of Alzheimer's disease[1].

Product Specifications

CAS Number

[223130-61-8]

UNSPSC

12352005

Target

Cholinesterase (ChE) ; NO Synthase

Related Pathways

Immunology/Inflammation; Neuronal Signaling

Field of Research

Inflammation/Immunology; Neurological Disease

Smiles

O=C1N2C3=CC=C(O)C=C3C(N[C@H](C2=NC4=CC=CC=C41)C)=O

Molecular Formula

C17H13N3O3

Molecular Weight

307.30

References & Citations

[1]Zhang C, et al. Circumdatin D Exerts Neuroprotective Effects by Attenuating LPS-Induced Pro-Inflammatory Responses and Downregulating Acetylcholinesterase Activity In Vitro and In Vivo. Front Pharmacol. 2020 May 25;11:760.