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SEH-IN-22

SEH-IN-22 (Compound 1) is a soluble epoxide hydrolase (sEH) inhibitor (IC50 = 1.1 μM) found in Rubia philippinensis. sEH-IN-22 exhibits anti-inflammatory, analgesic and blood pressure-regulating effects. sEH-IN-22 can be used for the researches of inflammation, neurological and cardiovascular disease[1].

Product Specifications

CAS Number

[2305966-67-8]

UNSPSC

12352005

Target

Epoxide Hydrolase

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Inflammation/Immunology; Neurological Disease; Cardiovascular Disease

Smiles

OC1=C2[C@](CC=C(C2=O)C)([H])[C@H](C3=CC=CC=C31)O

Molecular Formula

C15H14O3

Molecular Weight

242.27

References & Citations

[1]Oh J, et al. NMR-Based Investigation of Hydrogen Bonding in a Dihydroanthracen-1 (4 H) one from Rubia philippinensis and Its Soluble Epoxide Hydrolase Inhibitory Potential. J Nat Prod. 2018 Nov 26;81 (11) :2429-2435.

Shipping Conditions

Room temperature

Scientific Category

Natural Products

Clinical Information

No Development Reported

Curated Selection

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