(3R,5R) -3,5-Dihydroxy-1,7-bis (3,4-dihydroxyphenyl) heptane 3-O-β-D-glucopyranoside
Selected Variant
HY-N16637
Size: 1 Each
(3R,5R) -3,5-Dihydroxy-1,7-bis (3,4-dihydroxyphenyl) heptane 3-O-β-D-glucopyranoside is a diarylheptanol glycoside compound isolated from Tacca plantaginea. (3R,5R) -3,5-Dihydroxy-1,7-bis (3,4-dihydroxyphenyl) heptane 3-O-β-D-glucopyranoside significantly inhibit TNF-α-induced NF-κB transcriptional activity (IC50 = 9.4 μM) . (3R,5R) -3,5-Dihydroxy-1,7-bis (3,4-dihydroxyphenyl) heptane 3-O-β-D-glucopyranoside significantly activates PPAR transcriptional activity (EC50 = 9.9 μM) and has a specific activating effect on PPAR β (δ) (EC50 = 23.1 μM) . (3R,5R) -3,5-Dihydroxy-1,7-bis (3,4-dihydroxyphenyl) heptane 3-O-β-D-glucopyranoside is non-toxic to cells at the tested concentration. (3R,5R) -3,5-Dihydroxy-1,7-bis (3,4-dihydroxyphenyl) heptane 3-O-β-D-glucopyranoside can be used for research on inflammatory conditions[1].
Product Specifications
CAS Number
408324-05-0
UNSPSC
12352005
Target
NF-κB; PPAR
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; NF-κB; Vitamin D Related/Nuclear Receptor
Field of Research
Inflammation/Immunology
Smiles
OC(C=C1CC[C@H](C[C@H](O)CCC2=CC(O)=C(C=C2)O)O[C@@H]3O[C@@H]([C@H]([C@@H]([C@H]3O)O)O)CO)=C(C=C1)O
Molecular Formula
C25H34O11
Molecular Weight
510.53
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Price
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
CD71 / Transferrin Receptor (TFRC) (TFRC/1396), CF594 conjugate, 0.1mg/mL
![RPS6 Mouse Monoclonal Antibody [A6B9]](https://cdn.genprice.uk/products/992/68dd1c8a061270361ea80d2e/imageurl/ha600084.webp)
MDM2 (MDM2/2414), CF647 conjugate, 0.1mg/mL
VEGF (Vascular Endothelial Growth Factor) (VG76e), CF647 conjugate, 0.1mg/mL
