Ent-Calquiquelignan E
Ent-Calquiquelignan E (Compound 8) is a flavonoid lignan compound. Ent-Calquiquelignan E can selectively inhibit diacylglycerol acyltransferase 1 (DGAT1) with an IC50 of 71.5 μM. Ent-Calquiquelignan E can be used for the research of metabolic diseas[1].
Product Specifications
CAS Number
[1292294-31-5]
UNSPSC
12352005
Target
Acyltransferase
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Metabolic Disease
Smiles
O=C1C2=C(O)C=C(O)C=C2OC(C3=CC(OC)=C(C(OC)=C3)O[C@@H](CO)[C@H](C4=CC=C(C=C4)O)O)=C1
Molecular Formula
C26H24O10
Molecular Weight
496.46
References & Citations
[1]Xu WH, et al. Six new sesquineolignans from the stems of Akebia quinate and their diacylglycerol acyltransferase activity. Fitoterapia. 2024 Dec;179:106221.
Shipping Conditions
Room temperature
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-N16614/
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
DGAT1
Curated Selection
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