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Ent-Calquiquelignan E

Ent-Calquiquelignan E (Compound 8) is a flavonoid lignan compound. Ent-Calquiquelignan E can selectively inhibit diacylglycerol acyltransferase 1 (DGAT1) with an IC50 of 71.5 μM. Ent-Calquiquelignan E can be used for the research of metabolic diseas[1].

Product Specifications

CAS Number

1292294-31-5

UNSPSC

12352005

Target

Acyltransferase

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Metabolic Disease

Smiles

O=C1C2=C(O)C=C(O)C=C2OC(C3=CC(OC)=C(C(OC)=C3)O[C@@H](CO)[C@H](C4=CC=C(C=C4)O)O)=C1

Molecular Formula

C26H24O10

Molecular Weight

496.46

References & Citations

[1]Xu WH, et al. Six new sesquineolignans from the stems of Akebia quinate and their diacylglycerol acyltransferase activity. Fitoterapia. 2024 Dec;179:106221.

Shipping Conditions

Room temperature

Scientific Category

Natural Products

Clinical Information

No Development Reported

Isoform

DGAT1

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