2,4-Dihydroxy-6-methoxy-3,5-diprenylacetophenone

2,4-Dihydroxy-6-methoxy-3,5-diprenylacetophenone (Compound 8) is an Acetophenone (HY-Y0989) derivative found in Acronychia oligophlebia. 2,4-Dihydroxy-6-methoxy-3,5-diprenylacetophenone exhibits anti-inflammatory and antioxidant activities. 2,4-Dihydroxy-6-methoxy-3,5-diprenylacetophenone can inhibit LPS (HY-D1056) -induced NO production (IC50 = 34.5 μM) and scavenge DPPH free radical (SC50 = 0.15 mM) . 2,4-Dihydroxy-6-methoxy-3,5-diprenylacetophenone can be used for the research of inflammation[1].

Product Specifications

CAS Number

[123999-38-2]

UNSPSC

12352005

Target

Drug Derivative; NO Synthase

Related Pathways

Immunology/Inflammation; Others

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Smiles

O=C(C)C1=C(OC)C(C/C=C(C)\C)=C(O)C(C/C=C(C)\C)=C1O

Molecular Formula

C19H26O4

Molecular Weight

318.41

References & Citations

[1]Chen NH, et al. New Acetophenone Derivatives from Acronychia oligophlebia and Their Anti-inflammatory and Antioxidant Activities. Chem Biodivers. 2018 May;15 (5) :e18000080.