Cis-Emodin-physcion bianthrone
Cis-Emodin-physcion bianthrone is a potent inhibitor of protein tyrosine phosphatase 1B (PTP1B), with an IC50 value of 7.29 μM. cis-Emodin-physcion bianthrone can be used for research on type 2 diabetes[1].
Product Specifications
CAS Number
1085706-32-6
UNSPSC
12352005
Target
Phosphatase
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Metabolic Disease
Smiles
O=C1C2=C(O)C=C(OC)C=C2[C@@]([C@]3([H])C4=CC(C)=CC(O)=C4C(C5=C(O)C=C(O)C=C53)=O)([H])C6=CC(C)=CC(O)=C61
Molecular Formula
C31H24O8
Molecular Weight
524.52
References & Citations
[1]Zhao Y, et al. Potential of Polygonum cuspidatum Root as an Antidiabetic Food: Dual High-Resolution α-Glucosidase and PTP1B Inhibition Profiling Combined with HPLC-HRMS and NMR for Identification of Antidiabetic Constituents. J Agric Food Chem. 2017 Jun 7;65 (22) :4421-4427.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
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