Acrofolione A
Acrofolione A is an acetophenone dimer isolated from Acronychia pendunculata with anticancer effects. Acrofolione A induces G0/G1 phase cell cycle arrest and apoptosis in human NALM-6 pre-B cell leukaemia cells. Acrofolione A can be used for leukaemia research[1].
Product Specifications
CAS Number
820975-61-9
UNSPSC
12352005
Target
Apoptosis; Caspase; PARP; Survivin
Related Pathways
Apoptosis; Cell Cycle/DNA Damage; Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
CC(C)CC(C1=C(C(C/C=C(C)\C)=C(C(C(C)=O)=C1O)OC)O)C2=C3C(CC(O3)C(C)(O)C)=C(C(C(C)=O)=C2O)O
Molecular Formula
C32H42O9
Molecular Weight
570.67
References & Citations
[1]Matsui T, et al. Acrofolione A and B, acetophenone dimers from Acronychia pendunculata, induce an apoptotic effect on human NALM-6 pre-B cell leukaemia cells. J Pharm Pharmacol. 2019 Mar;71 (3) :348-361.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
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