Muurol-4-ene-3,8-dione
Muurol-4-ene-3,8-dione (Compound 2), a sesquiterpene, is one of the main hepatotoxic components in Eupatorium adenophorum. Muurol-4-ene-3,8-dione has an inhibitory effect on the growth of both the normal human hepatocyte cell L02 and the human hepatocellular carcinoma cell HepG2 with IC50 values of 87.52 and 104.48 μM[1].
Product Specifications
CAS Number
105181-07-5
UNSPSC
12352211
Target
Others
Related Pathways
Others
Field of Research
Metabolic Disease
Smiles
[H][C@]12C=C(C(C[C@@]([C@H](C)CC([C@@H]2C(C)C)=O)1[H])=O)C
Molecular Formula
C15H22O2
Molecular Weight
234.33
References & Citations
[1]Liu B, Cao L, Zhang L, Yuan X, Zhao B. Hepatotoxicity of Eupatorium adenophorum extracts and the identification of major hepatotoxic components. Nat Prod Res. 2017 Dec;31 (23) :2788-2792.|[2]Liu B, Cao L, Zhang L, Yuan X, Zhao B. Hepatotoxicity of Eupatorium adenophorum extracts and the identification of major hepatotoxic components. Nat Prod Res. 2017 Dec;31 (23) :2788-2792.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Frequently Asked Questions
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