3-Hydroxyphloridzin

3-Hydroxyphloridzin (3-Hydroxyphlorizin) is a protein tyrosine phosphatase 1B (PTP1B) inhibitor. 3-Hydroxyphloridzin modulates insulin receptor phosphorylation levels. 3-Hydroxyphloridzin is promising for research of type 2 diabetes[1].

Product Specifications

CAS Number

[30779-02-3]

Product Name Alternative

3-Hydroxyphlorizin

UNSPSC

12352005

Target

Phosphatase

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Metabolic Disease

Smiles

OC(C=C1CCC(C2=C(C=C(C=C2O)O)O[C@@H]3O[C@@H]([C@H]([C@@H]([C@H]3O)O)O)CO)=O)=C(C=C1)O

Molecular Formula

C21H24O11

Molecular Weight

452.41

References & Citations

[1]Pompermaier L, et al. Dihydrochalcone Glucosides from the Subaerial Parts of Thonningia sanguinea and Their in Vitro PTP1B Inhibitory Activities. J Nat Prod. 2018 Sep 28;81 (9) :2091-2100.