3-Hydroxyphloridzin
3-Hydroxyphloridzin (3-Hydroxyphlorizin) is a protein tyrosine phosphatase 1B (PTP1B) inhibitor. 3-Hydroxyphloridzin modulates insulin receptor phosphorylation levels. 3-Hydroxyphloridzin is promising for research of type 2 diabetes[1].
Product Specifications
CAS Number
[30779-02-3]
Product Name Alternative
3-Hydroxyphlorizin
UNSPSC
12352005
Target
Phosphatase
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Metabolic Disease
Smiles
OC(C=C1CCC(C2=C(C=C(C=C2O)O)O[C@@H]3O[C@@H]([C@H]([C@@H]([C@H]3O)O)O)CO)=O)=C(C=C1)O
Molecular Formula
C21H24O11
Molecular Weight
452.41
References & Citations
[1]Pompermaier L, et al. Dihydrochalcone Glucosides from the Subaerial Parts of Thonningia sanguinea and Their in Vitro PTP1B Inhibitory Activities. J Nat Prod. 2018 Sep 28;81 (9) :2091-2100.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Curated Selection
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