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Echihumiline

Echihumiline is an alkaloid targeting hepatic cytochrome P450 enzymes (CYP450) . Echihumiline induces DNA cross-linking and oxidative stress in hepatocytes, leading to liver necrosis and fibrosis. Echihumiline is promising for research of liver diseases[1].

Product Specifications

CAS Number

[174285-73-5]

UNSPSC

12352005

Target

Cytochrome P450

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Metabolic Disease

Smiles

O=C(/C=C(C)/C)O[C@H]1[C@@]2([H])C(COC([C@@]([C@@H](O)C)(C(O)(C)C)O)=O)=CCN2CC1

Molecular Formula

C20H31NO7

Molecular Weight

397.46

References & Citations

[1]Kretsi O, et al. Pyrrolizidine alkaloids from Onosma leptantha[J]. Helvetica chimica acta, 2003, 86 (9) : 3136-3140.

Shipping Conditions

Room temperature

Scientific Category

Natural Products

Clinical Information

No Development Reported

Curated Selection

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