(+) -Catechin 3-gallate
(+) -Catechin 3-gallate is an orally active polyphenolic compound that acts as a non-selective proteasome inhibitor. (+) -Catechin 3-gallate exerts antitumor effects by inducing apoptosis and suppressing inflammatory cytokines. (+) -Catechin 3-gallate is promising for research of cancers (e.g., breast, prostate) and neurodegenerative diseases (e.g., Alzheimer’s) [1].
Product Specifications
CAS Number
[25615-05-8]
UNSPSC
12352005
Target
Proteasome
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-Kinase/protease
Field of Research
Cancer; Neurological Disease
Smiles
O=C(C1=CC(O)=C(C(O)=C1)O)O[C@@H]2[C@@H](C3=CC(O)=C(C=C3)O)OC4=CC(O)=CC(O)=C4C2
Molecular Formula
C22H18O10
Molecular Weight
442.37
References & Citations
[1]Haslam E. (+) -catechin-3-gallate and a polymeric proanthocyanidin from Bergenia species. J Chem Soc Perkin 1. 1969;14:1824-8.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
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