Neoaspergillic acid

Neoaspergillic acid (NSC 356436) (Compound 2) is a microbial secondary metabolite. Neoaspergillic acid can be isolated from the endophytic fungus Aspergillus sp. SPH2. Neoaspergillic acid has potent antifungal activity against Alternaria alternata, Botrytis cinerea and Fusarium oxysporum. Neoaspergillic acid appears during the exponential phase of fungal growth. Neoaspergillic acid also antitumor and antibacterial effects[1][2].

Product Specifications

CAS Number

[2152-59-2]

Product Name Alternative

NSC 356436

UNSPSC

12352005

Target

Bacterial; Endogenous Metabolite; Fungal

Related Pathways

Anti-infection; Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Infection

Smiles

[O-][N+]1=C(C(CC(C)C)=NC=C1CC(C)C)O

Molecular Formula

C12H20N2O2

Molecular Weight

224.30

References & Citations

[1]Reyes Castillo N, et al. Optimization of fungicidal and acaricidal metabolite production by endophytic fungus Aspergillus sp. SPH2. Bioresour Bioprocess. 2024 Mar 5;11 (1) :28.|[2]Morales-Sánchez V, et al. Bioactive Metabolites from the Endophytic Fungus Aspergillus sp. SPH2. J Fungi (Basel) . 2021 Feb 2;7 (2) :109.