Mer-NF5003E
Mer-NF5003E is a non-nucleoside reverse transcriptase inhibitor targeting HIV-1 reverse transcriptase (RT) (EC50=50 μM) . Mer-NF5003E exhibits inhibitory activity against wild-type HIV-1 and multiple NNRTI-resistant strains (e.g., K103N, Y181C) . Mer-NF5003E is promising for research of HIV infections[1].
Product Specifications
CAS Number
159121-98-9
UNSPSC
12352005
Target
HIV; HIV Protease
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Field of Research
Infection
Smiles
C[C@@]12[C@@]3([C@@H](CC[C@@]1([H])C(C)([C@@H](CC2)O)C)C)OC4=C(C=O)C(CO)=CC(O)=C4C3
Molecular Formula
C23H32O5
Molecular Weight
388.50
References & Citations
[1]Ma X, et al. Phenylspirodrimanes with anti-HIV activity from the sponge-derived fungus Stachybotrys chartarum MXH-X73. J Nat Prod. 2013 Dec 27;76 (12) :2298-306.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Frequently Asked Questions
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