N-cis-Dodec-5 (Z) -enoyl-L-homoserine lactone

N-cis-Dodec-5 (Z) -enoyl-L-homoserine lactone (5-cis-C12-HSL) (Compound 2) is an acylated homoserine lactone. N-cis-Dodec-5 (Z) -enoyl-L-homoserine lactone can be isolated for Mesorhizobium sp. N-cis-Dodec-5 (Z) -enoyl-L-homoserine lactone restores protease and pyoverdin production of an AHL-deficient Pseudomonas aeruginosa PAO1 lasI rhlI double mutant. N-cis-Dodec-5 (Z) -enoyl-L-homoserine lactone has no significant antibacterial activity and cytotoxicity against tumor cells[1].

Product Specifications

CAS Number

[945495-73-8]

Product Name Alternative

5-cis-C12-HSL

UNSPSC

12352005

Target

Bacterial

Related Pathways

Anti-infection

Field of Research

Infection

Smiles

CCCCCC/C=C\CCCC(N[C@@H]1C(OCC1)=O)=O

Molecular Formula

C16H27NO3

Molecular Weight

281.39

References & Citations

[1]Krick A, et al. A marine Mesorhizobium sp. produces structurally novel long-chain N-acyl-L-homoserine lactones. Appl Environ Microbiol. 2007 Jun;73 (11) :3587-94.