Aspergillusidone F
Aspergillusidone F (Compound 3), a brominated depsidone, is a regioisomer of Aspergillusidone D. Aspergillusidone F is a Aromatase inhibitor with an IC50 of 0.5 μM. Aspergillusidone F can be isolated from fungus Aspergillus unguis cultured in KBr medium. Aspergillusidone F has potent cytotoxicity against cancers cells, such as MOLT-3 cells. Aspergillusidone F can be used for cancers like breast cancer research[1].
Product Specifications
CAS Number
1558007-47-8
UNSPSC
12352005
Target
Cytochrome P450; Drug Isomer; Endogenous Metabolite
Related Pathways
Metabolic Enzyme/Protease; Others
Field of Research
Cancer
Smiles
C/C=C(C1=C2C(OC(C3=C(C)C=C(O)C(Br)=C3O2)=O)=C(C(O)=C1Br)C)\C
Molecular Formula
C19H16Br2O5
Molecular Weight
484.14
References & Citations
[1]Sureram S, et al. Directed biosynthesis through biohalogenation of secondary metabolites of the marine-derived fungus Aspergillus unguis[J]. RSC advances, 2013, 3 (6) : 1781-1788.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
Aromatase/CYP19A1; Microbial Metabolite
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