Aspergillusidone F

Aspergillusidone F (Compound 3), a brominated depsidone, is a regioisomer of Aspergillusidone D (HY-N16402) . Aspergillusidone F is a Aromatase inhibitor with an IC50 of 0.5 μM. Aspergillusidone F can be isolated from fungus Aspergillus unguis cultured in KBr medium. Aspergillusidone F has potent cytotoxicity against cancers cells, such as MOLT-3 cells. Aspergillusidone F can be used for cancers like breast cancer research[1].

Product Specifications

CAS Number

[1558007-47-8]

UNSPSC

12352005

Target

Cytochrome P450; Drug Isomer; Endogenous Metabolite

Related Pathways

Metabolic Enzyme/Protease; Others

Field of Research

Cancer

Smiles

C/C=C(C1=C2C(OC(C3=C(C)C=C(O)C(Br)=C3O2)=O)=C(C(O)=C1Br)C)\C

Molecular Formula

C19H16Br2O5

Molecular Weight

484.14

References & Citations

[1]Sureram S, et al. Directed biosynthesis through biohalogenation of secondary metabolites of the marine-derived fungus Aspergillus unguis[J]. RSC advances, 2013, 3 (6) : 1781-1788.