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Aspergillusidone D

Aspergillusidone D (Compound 1), a brominated depsidone, is a Aromatase inhibitor with an IC50 of 0.8 μM. Aspergillusidone D can be isolated from fungus Aspergillus unguis cultured in KBr medium. Aspergillusidone D has potent cytotoxicity against cancers cells, such as MOLT-3 cells. Aspergillusidone D can be used for cancers like breast cancer research[1].

Product Specifications

CAS Number

1454585-77-3

UNSPSC

12352005

Target

Cytochrome P450; Endogenous Metabolite

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Cancer

Smiles

C/C=C(C1=C2C(OC(C3=C(C)C(Br)=C(O)C=C3O2)=O)=C(C(O)=C1Br)C)\C

Molecular Formula

C19H16Br2O5

Molecular Weight

484.14

References & Citations

[1]Sureram S, et al. Directed biosynthesis through biohalogenation of secondary metabolites of the marine-derived fungus Aspergillus unguis[J]. RSC advances, 2013, 3 (6) : 1781-1788.

Shipping Conditions

Room temperature

Scientific Category

Natural Products

Clinical Information

No Development Reported

Isoform

Aromatase/CYP19A1

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