(3R,6S) -Bassiatin

(3R,6S) -Bassiatin (Compound 5) is an enantiomer of the fungal metabolite Bassiatin (HY-165143) . Bassianin is a compound isolated from fungi that has the activity of inhibiting erythrocyte membrane ATPase and causing cell lysis. Its inhibitory effect on ATPase may be due to membrane disruption[1][2].

Product Specifications

CAS Number

[172721-96-9]

UNSPSC

12352005

Target

ATP Synthase; Drug Metabolite; Fungal

Related Pathways

Anti-infection; Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease

Field of Research

Infection

Smiles

CN(C([C@@H](OC1=O)C(C)C)=O)[C@@H]1CC2=CC=CC=C2

Molecular Formula

C15H19NO3

Molecular Weight

261.32

References & Citations

[1]Jeffs LB, et al. Toxic properties of Beauveria pigments on erythrocyte membranes. Toxicon. 1997 Aug;35 (8) :1351-6. |[2]Kagamizono T, et al. Bassiatin, a new platelet aggregation inhibitor produced by Beauveria bassiana K-717. J Antibiot (Tokyo) . 1995 Dec;48 (12) :1407-12.