ER-Laurdan
ER-Laurdan, a derivative of Laurdan (HY-D0080), is a fluorescent probe. ER-Laurdan contains a pentafluorophenyl (PFP) group with a PEG10 linker; the PFP group reacts with thiols in unfolded proteins in the ER and the linker provides flexibility for the protein-bound probe to integrate into the membrane. ER-Laurdan can be used to the study of the endoplasmic reticulum[1].
Product Specifications
CAS Number
[3091879-77-2]
UNSPSC
12352005
Target
Fluorescent Dye
Related Pathways
Others
Field of Research
Others
Purity
99
Smiles
O=C(C1=C(F)C(F)=C(F)C(F)=C1F)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(CN(C)C2=CC=C3C(C=CC(C(CCCCCCCCCCC)=O)=C3)=C2)=O
Molecular Formula
C54H80F5N3O13
Molecular Weight
1074.22
References & Citations
[1]Wong AM, et al. Organelle-targeted Laurdans measure heterogeneity in subcellular membranes and their responses to saturated lipid stress. bioRxiv [Preprint]. 2024 Apr 20:2024.04.16.589828. doi: 10.1101/2024.04.16.589828. Update in: ACS Chem Biol. 2024 Aug 16;19 (8) :1773-1785.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light)
Scientific Category
Dye Reagents
Clinical Information
No Development Reported
Curated Selection
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