Mito-laurdan (bromide)

Mito-laurdan bromide, a derivative of Laurdan (HY-D0080), is a fluorescent probe. Mito-laurdan bromide contains a cationic triphenylphosphonium moiety, which accumulates at the inner mitochondrial membrane due to its negative membrane potential, connected via a 3 carbon linker[1].

Product Specifications

CAS Number

[3091879-75-0]

UNSPSC

12352005

Target

Fluorescent Dye

Related Pathways

Others

Field of Research

Others

Smiles

O=C(CN(C)C1=CC2=CC=C(C(CCCCCCCCCCC)=O)C=C2C=C1)NCCC[P+](C3=CC=CC=C3)(C4=CC=CC=C4)C5=CC=CC=C5.[Br-]

Molecular Formula

C46H56BrN2O2P

Molecular Weight

779.83

References & Citations

[1]Wong AM, et al. Organelle-targeted Laurdans measure heterogeneity in subcellular membranes and their responses to saturated lipid stress. bioRxiv [Preprint]. 2024 Apr 20:2024.04.16.589828. doi: 10.1101/2024.04.16.589828. Update in: ACS Chem Biol. 2024 Aug 16;19 (8) :1773-1785.