Chloranthalactone C

Chloranthalactone C (Compound 43), a lindenane-type sesquiterpenoid, is an antimalarial agent. Chloranthalactone C can be isolated from plant Chloranthus japonicas Sieb. Chloranthalactone C inhibits Chloroquine (HY-17589A) -resistant Plasmodium falciparum strain Dd2 growth. Chloranthalactone C can be used for parasitic infections research[1][2].

Product Specifications

CAS Number

[73215-91-5]

UNSPSC

12352100

Target

Parasite

Related Pathways

Anti-infection

Field of Research

Infection

Smiles

C[C@]12[C@@]3([H])[C@]([C@H]([C@]1([H])CC(C(O4)=C2)=C(C)C4=O)COC(C)=O)([H])C3

Molecular Formula

C17H20O4

Molecular Weight

288.34

References & Citations

[1]Lu QQ, et al. Crystal structure and Hirshfeld analysis of (1aS,3aR,4aS,5aR) -15-acet-oxy-linden-7 (11),8-trieno-12,8-lactone. Acta Crystallogr E Crystallogr Commun. 2022 May 20;78 (Pt 6) :642-646. |[2]Zhou B, et al. Nanomolar Antimalarial Agents against Chloroquine-Resistant Plasmodium falciparum from Medicinal Plants and Their Structure-Activity Relationships. J Nat Prod. 2017 Jan 27;80 (1) :96-107.