Cochliomycin A
Cochliomycin A ((+) -Cochliomycin A) can be isolated from Gorgonian-Derived Fungus Cochliobolus lunatus. Cochliomycin A has antifouling activity (EC50: 1.2 μg/mL) . Cochliomycin A inhibits barnacle larval settlement by stimulating the NO/cGMP pathway. Cochliomycin A also has moderate antibacterial activity against S. aureus[1][2].
Product Specifications
CAS Number
1278520-07-2
Product Name Alternative
(+) -Cochliomycin A
UNSPSC
12352005
Target
Bacterial
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
OC1=C(C(O[C@H](C/C=C/[C@@](O2)([H])[C@@]3([H])OC2(C)C)C)=O)C(/C=C/C[C@@H]3O)=CC(OC)=C1
Molecular Formula
C22H28O7
Molecular Weight
404.45
References & Citations
[1]Shao CL, et al. Potent antifouling resorcylic acid lactones from the gorgonian-derived fungus Cochliobolus lunatus. J Nat Prod. 2011 Apr 25;74 (4) :629-33. |[2]Wang KL, et al. Cochliomycin A inhibits the larval settlement of Amphibalanus amphitrite by activating the NO/cGMP pathway. Biofouling. 2016;32 (1) :35-44.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
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