Cochliomycin A

Cochliomycin A ((+) -Cochliomycin A) can be isolated from Gorgonian-Derived Fungus Cochliobolus lunatus. Cochliomycin A has antifouling activity (EC50: 1.2 μg/mL) . Cochliomycin A inhibits barnacle larval settlement by stimulating the NO/cGMP pathway. Cochliomycin A also has moderate antibacterial activity against S. aureus[1][2].

Product Specifications

CAS Number

[1278520-07-2]

Product Name Alternative

(+) -Cochliomycin A

UNSPSC

12352005

Target

Bacterial

Related Pathways

Anti-infection

Field of Research

Infection

Smiles

OC1=C(C(O[C@H](C/C=C/[C@@](O2)([H])[C@@]3([H])OC2(C)C)C)=O)C(/C=C/C[C@@H]3O)=CC(OC)=C1

Molecular Formula

C22H28O7

Molecular Weight

404.45

References & Citations

[1]Shao CL, et al. Potent antifouling resorcylic acid lactones from the gorgonian-derived fungus Cochliobolus lunatus. J Nat Prod. 2011 Apr 25;74 (4) :629-33. |[2]Wang KL, et al. Cochliomycin A inhibits the larval settlement of Amphibalanus amphitrite by activating the NO/cGMP pathway. Biofouling. 2016;32 (1) :35-44.