Ethyl salvianolate A

Ethyl salvianolate A (Ethyl salvionolate A) is an anti-HIV-1 compound that can be extracted from the roots of Salvia yunnanensis. Ethyl salvianolate A inhibits P24 antigen in HIV-1 infected MT-4 cell cultures (EC50: 1.44 μg/mL) . Ethyl salvianolate A inhibits HIV-1 replicative enzymes, with IC50s of 56.38 μM (Reverse transcriptase), 12.03 μM (Protease), 14.54 μM (Integrase), respectively[1].

Product Specifications

CAS Number

[1015171-68-2]

Product Name Alternative

Ethyl salvionolate A

UNSPSC

12352005

Target

HIV; HIV Integrase; HIV Protease; Reverse Transcriptase

Related Pathways

Anti-infection; Metabolic Enzyme/Protease

Field of Research

Infection

Purity

91.38

Solubility

DMSO : 100 mg/mL

Smiles

OC(C=C1/C=C/C2=C(C=CC(O)=C2O)/C=C/C(O[C@@H](C(OCC)=O)CC3=CC(O)=C(C=C3)O)=O)=C(C=C1)O

Molecular Formula

C28H26O10

Molecular Weight

522.50

References & Citations

[1]Zhang ZF, et al. Three new derivatives of anti-HIV-1 polyphenols isolated from Salvia yunnanensis. J Asian Nat Prod Res. 2008 May-Jun;10 (5-6) :391-6.