TAN-1030A
TAN-1030A is an indolocarbazole alkaloid with macrophage-activating properties. TAN-1030A induces spreading of a murine macrophage cell line, Mm 1, and augmentes the phagocytic activity, Fc gamma receptor expression and β-glucuronidase activity of murine macrophage cell lines, Mm 1 and J774A.1. TAN-1030A can activate macrophage functions in mice[1].
Product Specifications
CAS Number
126221-76-9
UNSPSC
12352005
Target
β-glucuronidase
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Inflammation/Immunology
Purity
95.04
Solubility
DMSO : 3.33 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
C[C@]12N3C4=C(C5=CC=CC=C53)C(CNC6=O)=C6C7=C4N([C@](C/C([C@H]2OC)=N/O)([H])O1)C8=CC=CC=C78
Molecular Formula
C27H22N4O4
Molecular Weight
466.49
References & Citations
[1]Tanida S, et al. TAN-999 and TAN-1030A, new indolocarbazole alkaloids with macrophage-activating properties. J Antibiot (Tokyo) . 1989 Nov;42 (11) :1619-30.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
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