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TAN-1030A

TAN-1030A is an indolocarbazole alkaloid with macrophage-activating properties. TAN-1030A induces spreading of a murine macrophage cell line, Mm 1, and augmentes the phagocytic activity, Fc gamma receptor expression and β-glucuronidase activity of murine macrophage cell lines, Mm 1 and J774A.1. TAN-1030A can activate macrophage functions in mice[1].

Product Specifications

CAS Number

126221-76-9

UNSPSC

12352005

Target

β-glucuronidase

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Inflammation/Immunology

Purity

95.04

Solubility

DMSO : 3.33 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

C[C@]12N3C4=C(C5=CC=CC=C53)C(CNC6=O)=C6C7=C4N([C@](C/C([C@H]2OC)=N/O)([H])O1)C8=CC=CC=C78

Molecular Formula

C27H22N4O4

Molecular Weight

466.49

References & Citations

[1]Tanida S, et al. TAN-999 and TAN-1030A, new indolocarbazole alkaloids with macrophage-activating properties. J Antibiot (Tokyo) . 1989 Nov;42 (11) :1619-30.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Natural Products

Clinical Information

No Development Reported

Frequently Asked Questions

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