Cholyl-Lys-fluorescein (sodium)

Cholyl-Lys-fluorescein sodium is a fluorescein-labeled bile acid analog. Cholyl-Lys-fluorescein sodium can be used for biliary atresia validation and for determining in vivo liver function[1][2].

Product Specifications

UNSPSC

12352211

Target

Fluorescent Dye

Related Pathways

Others

Field of Research

Metabolic Disease

Smiles

O=C(C1=CC(NC(NCCCC[C@@H](C(O[Na])=O)NC(CC[C@H]([C@]2([H])[C@@]3([C@@]([C@@]4([H])[C@]([C@@]5([C@](C[C@@H](CC5)O)([H])C[C@H]4O)C)([H])C[C@@H]3O)([H])CC2)C)C)=O)=O)=CC=C1C(C6=CC(O)=CC=C6O7)=C(C=C8)C7=CC8=O)O[Na]

Molecular Formula

C51H61N3Na2O12

Molecular Weight

954.02

References & Citations

[1]de Waart DR, et al. Hepatic transport mechanisms of cholyl-L-lysyl-fluorescein. J Pharmacol Exp Ther. 2010 Jul;334 (1) :78-86.|[2]Mills CO, et al. Cholyl-lysylfluorescein: synthesis, biliary excretion in vivo and during single-pass perfusion of isolated perfused rat liver. Biochim Biophys Acta. 1991 Dec 6;1115 (2) :151-6.