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VSA 2

VSA 2, a saponin-based vaccine adjuvant, is a derivative of Momordica saponin (MS) II. VSA 2 is an immunostimulant, shows consistent enhancement of immunoglobulin G2a (IgG2a) production when it was in formulation with either ovalbumin or recombinant hemagglutinin B (rHagB) antigen[1].

Product Specifications

CAS Number

[2489675-56-9]

UNSPSC

12352005

Target

Biochemical Assay Reagents

Related Pathways

Others

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Smiles

O[C@H]([C@@H]([C@H]([C@@H](O1)C)O[C@H]2[C@@H]([C@H]([C@@H](CO2)O)O)O)O[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O[C@H]4[C@@H]([C@H]([C@@H](CO4)O)O)O)O)[C@@H]1O[C@H]([C@H]([C@H]([C@H](O5)C)O)O)[C@@H]5OC([C@]67[C@](CC(C)(CC7)C)([H])C8=CC[C@@]([C@@]9([C@@]([C@@](C)([C@H](CC9)O[C@H]%10[C@@H]([C@H]([C@@H]([C@H](O%10)C(NCCCCCCCCCCC(OCC%11=CC=CC=C%11)=O)=O)O)O[C@H]%12[C@@H]([C@@H]([C@H]([C@@H](O%12)C)O)O)O)O[C@@H]%13O[C@@H]([C@@H]([C@@H]([C@H]%13O)O)O)CO)C=O)([H])CC%14)C)([H])[C@]%14(C)[C@@]8(C[C@H]6O)C)=O

Molecular Formula

C94H147NO42

Molecular Weight

1963.15

References & Citations

[1]Wang P, et al. Structural Effect on Adjuvanticity of Saponins. J Med Chem. 2020 Mar 26;63 (6) :3290-3297.

Shipping Conditions

Room temperature

Scientific Category

Natural Products

Clinical Information

No Development Reported

Curated Selection

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