Amorphispironone

Amorphispironone (Compound 1) is a rotenoid that can be isolated the leaves of A. fruticosa. Amorphispironone exhibits remarkable inhibitory effects on EBV-EA activation induced by TPA. Amorphispironone exhibits potent anti-tumor-promotion activity on mouse skin tumor promotion in vivo[1].

Product Specifications

CAS Number

[139006-28-3]

UNSPSC

12352005

Target

EBV

Related Pathways

Anti-infection

Field of Research

Cancer

Smiles

CC(O1)(C)C=CC2=C1C=CC3=C2O[C@@]4([H])[C@@]([C@@](C5=O)(C=C(OC)C(OC)=C5)OC4)([H])C3=O

Molecular Formula

C23H22O7

Molecular Weight

410.42

References & Citations

[1]Konoshima, T., et al., (1993) . Studies on inhibitors of skin tumor promotion, XII. Rotenoids from Amorpha fruticosa. Journal of natural products, 56 (6), 843–848.