Anti-Heart Failure Agent 3

Anti-Heart Failure Agent 3 (Compound 2) is an anti-heart failure agent with anti-inflammatory activity found in processed Cornus officinalis. Anti-Heart Failure Agent 3 inhibits NO release in LPS-induced RAW264.7 cells. Anti-Heart Failure Agent 3 alleviates myocardial ischemia-reperfusion injury, reduces myocardial infarction size, and improves myocardial histopathological changes. Anti-Heart Failure Agent 3 is promising for research of heart failure[1].

Product Specifications

CAS Number

[2901143-47-1]

UNSPSC

12352211

Target

NO Synthase

Related Pathways

Immunology/Inflammation

Field of Research

Cardiovascular Disease

Smiles

COC([C@H](O)CC(OCC1=CC=C(C(O)=O)O1)=O)=O

Molecular Formula

C11H12O8

Molecular Weight

272.21

References & Citations

[1]Dai LP, et al. Preparation method and application of three compounds separated from Cornus officinalis and having heart failure prevention and treatment effects. CN115073403A. 2023-12-22.