Fukinolic acid
Fukinolic acid is a benzyltartaric acid ester, is a vasodilator with antiviral activity against enterovirus A71 (EV-A71) replication. Fukinolic acid is a receptor-operated Ca2+ channels (ROC) inhibitor, suppressing extracellular Ca2+ influx through ROC activated by Norepinephrine without affecting voltage-dependent Ca2+ channels[1][2].
Product Specifications
CAS Number
50982-40-6
UNSPSC
12352005
Target
Calcium Channel; Enterovirus
Related Pathways
Anti-infection; Membrane Transporter/Ion Channel; Neuronal Signaling
Field of Research
Infection; Cardiovascular Disease
Smiles
OC(C=C1C[C@@](C(O)=O)(O)[C@@H](C(O)=O)OC(/C=C/C2=CC(O)=C(C=C2)O)=O)=C(C=C1)O
Molecular Formula
C20H18O11
Molecular Weight
434.35
References & Citations
[1]Noguchi M, et al. Vasoactive effects of cimicifugic acids C and D, and fukinolic acid in cimicifuga rhizome. Biol Pharm Bull. 1998;21 (11) :1163-1168|[2]Ma Y, et al. Identification of fukinolic acid from Cimicifuga heracleifolia and its derivatives as novel antiviral compounds against enterovirus A71 infection. Int J Antimicrob Agents. 2019;53 (2) :128-136.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Frequently Asked Questions
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