Petiline
Petiline is a steroidal alkaloid found in Petilium raddeanum, acting as a selective antagonist of M cholinergic receptors. Petiline exerts anticholinergic effects (e.g., reducing vagal influence on the heart) by competitively blocking M cholinergic receptors, and also has central excitatory, cardiotonic, and spasmolytic activities. Petiline is promising for research of cholinergic system-related diseases (e.g., arrhythmia, intestinal spasm) [1].
Product Specifications
CAS Number
26989-18-4
UNSPSC
12352211
Target
MAChR
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Neurological Disease
Smiles
C[C@@]12[C@](CC[C@]2([H])[C@@H](C3=NC[C@@H](C)CC3)C)([H])[C@@]4([H])[C@@](CC1)([H])[C@@]5([C@@](C[C@H](CC5)O)([H])C(C4)=O)C
Molecular Formula
C27H43NO2
Molecular Weight
413.64
References & Citations
[1]Mirzaev Y R. Pharmacologic Properties of Certain Steroidal Alkaloids of Varying Structure[J]. Chemistry of natural compounds, 2004, 40 (4) .
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
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